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==== 6.4.2.3 Impacts on the Human System ==== <div id="section-6-4-2-3impacts-on-the-human-system-block-1"></div> MHWs can also lead to significant socioeconomic ramifications when affecting aquaculture or important fishery species, or when triggering heavy rain or drought events on land. The Northwest Atlantic 2012 MHW, for example, had major economic impacts on the US lobster industry in 2015 (Mills et al., 2013). The MHWs lead to changes in lobster fishing practices and harvest patterns, because the lobsters moved from the deep offshore waters into shallower coastal areas much earlier in the season than usual causing a rapid rise in lobster catch rates. Together with a supply chain bottleneck, the record catch outstripped market demand and contributed to a collapse in lobster prices (Mills et al., 2013 <sup>[[#fn:r453|453]]</sup> ). Even though high catch volumes were reported, the price collapse threatened the economic viability of many US and Canadian lobster fisheries. Economic impacts through changes in fisheries were also reported during the Northeast Pacific 2013β2015 MHW and the Alaskan Sea 2016 MHW. The Northeast Pacific 2013β2015 MHW led to closing of both commercial and recreational fisheries resulting in millions of USD in losses among fishing industries (Cavole et al., 2016 <sup>[[#fn:r455|455]]</sup> ). In addition, the toxin produced by the harmful algal blooms can be transferred through the marine food web and humans who eat contaminated fish, shellfish or crustaceans (Berdalet et al., 2016 <sup>[[#fn:r456|456]]</sup> ; Du et al., 2016 <sup>[[#fn:r457|457]]</sup> ; McCabe et al., 2016 <sup>[[#fn:r458|458]]</sup> ). The ingestion of such contaminated seafood products, the inhalation of aerosolised toxins or the skin contact with toxin-contaminated water may cause toxicity in humans. Symptoms in human associated with the ingestion of the contaminated seafood range from mild gastrointestinal distress to seizures, coma, permanent short-term memory loss and death (Perl et al., 1990 <sup>[[#fn:r459|459]]</sup> ). The ecological changes associated with the Alaskan Sea 2016 MHW impacted subsistence and commercial activities. For example, ice-based harvesting of seals, crabs and fish in western Alaska was delayed due to the lack of winter sea ice. MHWs can also impact the socioeconomic and human system through changes to weather patterns. For example, heavy rain associated with the Coastal Peruvian 2017 MHW triggered numerous landslides and flooding, which resulted in a death toll of several hundred, and widespread damage to infrastructure and civil works (United Nations, 2017 <sup>[[#fn:r460|460]]</sup> ). Studies on the impact of MHWs on human systems are still relatively scarce, even though many show negative impacts on human health and economy. We therefore conclude with ''medium confidence'' that MHWs can negatively impact human health and economy. <span id="risk-management-and-adaptation-monitoring-and-early-warning-systems"></span>
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