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IPCC:AR6/WGII/Chapter-7
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==== 7.2.3.2 Non-communicable Respiratory Diseases ==== <div id="h3-12-siblings" class="h3-siblings"></div> Lung diseases, including asthma, COPD and lung cancer, comprise the largest subsets of non-communicable pulmonary disease ( [[#Ferkol--2014|Ferkol and Schraufnagel, 2014]] ). Overall, the global burden of non-communicable lung disease including all chronic lung disease and lung cancer is substantial, being responsible for 10.6% of deaths and 5.9% of DALYs globally in 2019 (Vos et al., 2020). ''Several non-communicable respiratory diseases are climate sensitive based on their exposure pathways (very high confidence).'' Multiple exposure pathways contribute to non-communicable respiratory disease ( [[#Deng--2020|Deng et al., 2020]] ), some of which are climate-related ( [[#Rice--2014|Rice et al., 2014]] ), including mobilisation and transport of dust ( [[#Schweitzer--2018|Schweitzer et al., 2018]] ); changes in concentrations of air pollutants such as small particulates (PM2.5) and ozone formed by photochemical reactions sensitive to temperature ( [[#Hansel--2016|Hansel et al., 2016]] ); increased wildland fires and related smoke exposure ( [[#Johnston--2002|Johnston et al., 2002]] ; [[#Reid--2016|Reid et al., 2016]] ); increased exposure to ambient heat driving reduced lung function and exacerbations of chronic lung disease ( [[#Collaco--2018|Collaco et al., 2018]] ; [[#Jehn--2013|Jehn et al., 2013]] ; [[#McCormack--2016|McCormack et al., 2016]] ; [[#Witt--2015|Witt et al., 2015]] ) and modification of aeroallergen production and duration of exposure ( [[#Ziska--2019|Ziska et al., 2019]] ). ''Burdens of allergic disease, particularly allergic rhinitis and allergic asthma may be changing in response to climate change (medium confidence)'' ( [[#D’Amato--2020|D’Amato et al., 2020]] ; [[#Eguiluz-Gracia--2020|Eguiluz-Gracia et al., 2020]] ; [[#Deng--2020|Deng et al., 2020]] ; [[#Demain--2018|Demain, 2018]] ). This is supported by evidence showing an increase in the length of the North American pollen season attributable to climate change ( [[#Ziska--2019|Ziska et al., 2019]] ), an association between timing of spring onset and higher asthma hospitalisations presumed to be due to higher pollen exposure ( [[#Sapkota--2020|Sapkota et al., 2020]] ) and other evidence linking aeroallergen exposure with a worsening burden of allergic disease ( [[#Demain--2018|Demain, 2018]] ; [[#Poole--2019|Poole et al., 2019]] ). <div id="7.2.3.3" class="h3-container"></div> <span id="cancer"></span>
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